تسجيل الدخول

تسجيل

Human , Protein hormones

المؤلف:  Sue Jickells , Adam Negrusz (Editors)

المصدر:  Clarkes Analytical Forensic Toxicology

الجزء والصفحة:  269

2026-10-21

57

Human

Protein hormones

There has been considerable concern in recent years over the use of peptide hormones such as erythropoietin (EPO) and darbepoietin. EPO is a peptide hormone secreted in the kidneys. It has an important role in the regulation of blood cell production. Administration of EPO has been shown to increase erythrocyte production. EPO was originally used to treat patients suffering from kidney disease. These patients often developed anaemia as a result of disruption of EPO production. Athletes recognised the potential for EPO to increase erythrocyte production and hence oxygen uptake.

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced in the body, particularly during pregnancy. Administration of hCG stimulates testosterone production but does not raise the testosterone/epitestosterone ratio. Initially, this made hCG administration difficult to detect, but methods of detection have now been developed for use in human sports drug testing.