6:44:20 
2023-04-14 
514
Study: Some bacteria cells can become "hungry" like humans
A study finds that some bacteria cells can become "hungry" and irritable, just like humans.
Microbiologists have found that a lack of nutrients causes some bacterial cells to release harmful toxins into our bodies that can make us sick.
While the current study focused on just one bacterium, if the results are identical to other species, this could pave the way for new treatments for the infection, according to the study published in Nature Microbiology.
The study was conducted by microbiologist Professor Adam Rosenthal of the University of North Carolina at Chapel Hill and colleagues from Harvard and Princeton Universities, as well as Dutch pet food company Danisco.
Professor Rosenthal said: "Bacteria behave much differently than we have traditionally thought. Even when we study a community of genetically similar bacteria, they don't all behave in the same way. And we wanted to find out why."
The team used a newly developed analysis method called "probe-based bacterial sequencing" to read RNA molecules from thousands of individual bacteria.
The latter bacterial species are commonly found in nature and are a major cause of food poisoning.
The researchers suggested that genetically similar cells within the bacterial community have different functions, with some organs behaving more obediently while others produce toxins that make us feel sick.
Rosenthal decided to take a closer look at why some cells act as "well-behaved residents" and others as "bad actors" tasked with releasing toxins into the environment around them.
The team selected Clostridium perfringens (or C. perfringens), a bacterium that can be found in the intestines of humans, vertebrates, insects and soil, for the study. They were able to separate or divide single bacterial cells into droplets to decode each cell individually.
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